Goodpasture syndrome is an autoimmune disorder. It occurs when the immune system mistakenly attacks and destroys healthy body tissue. People with this syndrome develop substances that attack a protein called collagen in the tiny air sacs in the lungs and the filtering units of the kidneys.

Sometimes, this disorder is triggered by a viral respiratory infection, or by breathing in certain solvents. In such cases, the immune system may attack organs or tissues because it mistakes them for these viruses or foreign chemicals.

Symptoms may occur very slowly over months or even years, but they often develop very quickly over days to weeks.

  • Loss of appetite, fatigue, and weakness are common early symptoms.
  • Lung symptoms may include:
  • Coughing up blood
  • Dry cough
  • Shortness of breath
  • Kidney and other symptoms include:
  • Bloody urine
  • Burning sensation when urinating

Source: Mediline Plus